Ghrelin improves rat sperm kinematic parameters during abdominal position of the testis

نویسنده

  • Arash Kheradmand Department of Clinical Sciences, School of Veterinary Medicine, Lorestan University, Khorram Abad, Iran
چکیده مقاله:

BACKGROUND: Disruption of testicular function and arrest ofspermatogenesis are the consequence of cryptorchidism inresponse to elevated temperature. OBJECTIVES:This investigationwas set to clarify the possible ghrelin efficacy in altering somesperm quality parameters upon experimentally-induced cryptorchidism.METHODS: Thirty male adult rats were scheduled for thestudy and were divided into three groups: group 1 was served ascontrol-saline (CS), group 2 was designed as cryptorchidism-saline(CrS), and group 3 was defined as cryptorchidism-ghrelin (CrG).After surgically inducing cryptorchidism in groups 2 and 3, theresearchers gave 10 nmol of ghrelin to CrG rats for 7 consecutivedays. Five animals in each group were equally killed on days 3 and7 after operation and their testes were taken for sperm evaluation.RESULTS: Testicular weight, sperm forward progressive motility(FPM), functional membrane integrity (assessed by HOS-test), andsperm concentration displayed slight changes after heating on day3. However, abdominal position of the testes for 7 days caused asignificant reduction in the percentages of HOS-positive cells(p

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ghrelin improves rat sperm kinematic parameters during abdominal position of the testis

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عنوان ژورنال

دوره 8  شماره 2

صفحات  111- 117

تاریخ انتشار 2014-08-01

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